Category Archives: World News
A potential leap forward in the issue of post-treatment infertility.
The growth of new blood vessels – angiogenesis – occurs during the repair of damaged tissue and organs in adults. However, malignant tumors also grow new blood vessels in order to receive oxygen and nutrients. As such, angiogenesis is both beneficial and detrimental to health, depending on the context, requiring therapeutic approaches that can either help to stimulate or prevent it. Therapeutics that aim to prevent the growth of new blood vessels are already in use, but the results are often more modest than predicted.
For more than a decade, Prof Petri Salvén of the University of Helsinki and his colleagues have studied the mechanisms of angiogenesis to discover how blood vessel growth could be prevented or accelerated effectively.
“We succeeded in isolating endothelial cells with a high rate of division…
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To me, the stem cells within a germline are a perfect storm of fascination. Stem cells are, of course, intriguing in their ability to self-renew and differentiate, and a germline is intriguing in its ability to generate gametes. Add stem cells and germlines together, and you have amazing biology in front of you…and more biology […]
More good news from an often overlooked area of stem cell research, the impact of disease modelling in accelerating the production of new drugs and treatments
van Kopen et al reported a long term therapeutic rescue function in chronic kidney disease. An MSC produced conditioned medium, administered intravenously, decreased progression of CKD and reduced hypertension and glomerular injury.
In this study by Chae et al. published in the Biochemical Journal, 26 differentially expressed proteins were identified as being critical to the etiology of HD. In particular, superoxide dismutase 1 (SOD1) and peroxiredoxins are significantly affected, implying the significance of oxidative stress in HD.
Once again, the value of iPSC in disease modelling is demonstrated.
Challenging existing theories on vascular remodelling and diseases, a paper by Tang et al describes how multipotent vascular stem cells contribute to vascular remodelling by differentiating into smooth muscle cells and chondrogenic cells.
Image: Song Li